Typhoid vaccine pills side effects1/27/2024 Antimicrobial AgentsĪntimicrobial agents can be active against the vaccine strains in the oral typhoid and cholera vaccines and might prevent adequate immune response to these vaccines. A study in children using oral cholera vaccine suggested no decrease in immunogenicity when given with atovaquone-proguanil. Administer live attenuated oral cholera vaccine ≥10 days before beginning antimalarial prophylaxis with chloroquine. Data from an older formulation of the CVD 103-HgR oral cholera vaccine suggest that the immune response to the vaccine might be diminished when given concomitantly with chloroquine. ![]() Antimalarial DrugsĬhloroquine and atovaquone-proguanil at doses used for malaria chemoprophylaxis can be given concurrently with oral typhoid vaccine. Live attenuated vaccines generally should be avoided in immunocompromised travelers, including those taking antimetabolites, calcineurin inhibitors, cytotoxic agents, immunomodulators, and high-dose steroids (see Table 3-04). Travel Vaccines & Drugs Live Attenuated Oral Typhoid & Cholera Vaccines 3, Vaccination & Immunoprophylaxis-General Principles. However, certain vaccines, including pneumococcal and meningococcal vaccines and live virus vaccines, require appropriate spacing further information about vaccine–vaccine interactions is found in Sec. Most common vaccines can be given safely and effectively at the same visit, at separate injection sites, without impairing antibody response or increasing rates of adverse reactions. ![]() identified potential drug–drug interactions with travel-related medications in 45% of travelers taking medications for chronic conditions 3.5% of these interactions were potentially serious. Drugs Used for Travel to High Elevationsĭuring pretravel consultations, travel health providers must consider potential interactions between vaccines and medications, including those already taken by the traveler.
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